T-Bills

T-Bills t1_j0cyfxf wrote

It's the year 2077. Rudy has been dead for decades. A panel will finally unanimously agree after a 7-year deliberation with hundreds of witnesses and 2 million pages of testimony that it's highly probable that Rudy committed some ethically unsavory actions.

The panel has also voted in a bitterly divided fashion that further investigation by a new panel is warranted.

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T-Bills t1_iyctpjv wrote

Also in the article

> Dr. Jonathan Samuels, a rheumatologist at NYU Langone Health, said it’s tough to determine causation in studies like the two new ones, because many factors can influence the progression of arthritis and no two patients are the same.

> “We don’t have the biology to prove that the injection itself is causing accelerated damage. It’s hard to connect the dots from injection to damage from this preliminary data,” he said. “But it’s an important question, because it’s such a common practice to be injected with steroids.”

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T-Bills t1_isz094m wrote

I think the concern is how the immunogenicity from a booster dose would pan out over time. It deteriorates over time and this study was done to confirm that there is still a sufficient level of immunogenicity 3 months out. I wish they have more data at different time points, perhaps within a 12 month time span.

I think it's a legitimate concern whether one should "time" the booster shot to coincide with peak flu season. I believe study on the primary doses conclude that full immunogenicity is reached in about 2 weeks? You're also correct that one should consult your doctor for advice more relevant in your local area.

Edit: here's a CDC report

> During the period of Omicron predominance, VE against COVID-19–associated hospitalizations was lower overall and waned with time since vaccination: VE after a second dose declined from 71% within 2 months of vaccination to 54% among those vaccinated ≥5 months earlier (p = 0.01). Among recipients of 3 doses, VE against COVID-19–associated hospitalizations declined from 91% among those vaccinated within the past 2 months to 78% among those vaccinated ≥4 months earlier (p<0.001).

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