It will get approved when it is more efficient, less costly, and accurate than human clinical trials. Which will happen inevitably if we do reach the singularity

That’s pretty much what this sub is. We are all speculating what AI will do in the future. Do you believe the singularity is possible? If so, it’s an odd statement to make that therapies won’t be approved based on simulated trials. I doubt the FDA or any such regulatory bodies will even exist in the future. What’s the need for human regulations when we have super intelligence far beyond our own?

We already have organ on a chip models, so we already have the building blocks for simulating a human. At the point where trials on a simulated human can predict results as well as human clinical trials, I bet we stop using human clinical trials.

Since you work on human clinical trials, you would know that humans are very diverse and not every human responds the same way to a treatment. So it’s not like human clinical trials are even close to perfect. We can use technology to move past human clinical trials

He did mention in silico trials so I’m guessing he means being able to simulate human clinical trials so we can make it move faster. Not even close to possible now since we can’t simulate a human but perhaps in the future

There was a dude who automated his Tinder using AI I think. Saw it on tiktok a while ago

It used to be a lot more scientific in the past. The reason I joined reddit was to sub to longevity and singularity since I was interested in life extension and AI.

My background is in biology so I don’t understand AI very well, but when Alpha Fold came out I understood the significance of that and it’s implications on medicine and biology. There were great discussions on that here.

Unfortunately now there aren’t any scientific discussions on this sub anymore. It’s just a bunch of doomers and cultists arguing whether AI will be dystopic or utopic lol

I already unsubbed from futurology. My favorite sub is still r/longevity. Stays on topic for a big sub and the discussions are all scientific and the moderating team is great

Not really a good thing imo

I feel like this sub will turn into futurology as it gets bigger. Reddit is full of depressed doomers

I’ve been subbed to this sub for almost 2 years now I think and following it without an account for over 4 years, and the quality has already gone down. The knowledgeable people have either left or their voice has been diluted by the influx of commenters

Well for example I forgot my gfs birthday (more scared of her than a killer AGI tbh 😅) and I asked chatGpt what to do. It gave me tons of examples of things I can say, things I can do etc.

Ultimately it’s up to you to actually do it, but chatGPT can guide you in the right direction. It’s a great brainstorming tool.

I can’t wait for the day we have personalized AI assistants.

I’ve been using it to brainstorm ideas to solve any conflicts in my life.

Genuinely think chatGTP has higher social intelligence than me

Yeah but to make it to hospitals they need to go through 3 phases of human clinical trials by current standards, which can take up to a decade.

In the future we may be able to simulate human trials but that technology is not present currently

Yes in silico models will help greatly with this. With AGI we could develop in silico models pretty fast

It won’t because it has to make it through clinical trials. It might bring a lot more drugs/therapies into the pipeline though

Inferior as in there are so many negatives to the human experience, while in the future we may experience an existence without any negatives whatsoever.

Like sleeping and pooping as a simple (and not super negative) example. It’s unnecessary in a post human future.

Human relationships might not exist in the future, atleast not in the way you think.

I mean think about it, a decent amount of people will be uploaded into the cloud living in their own world. Very few people will remain human the way we are today. And to be fair why would you want to? It’s an inferior experience

Why the future will be better? Well you mentioned poverty. I think you should acknowledge the fact that poverty has been decreasing as technology increases.

Medical advances due to technology will greatly reduce suffering in the future.

And no this sub is not an echo chamber but I don’t want it to be another futurology which is just filled with a bunch of ignorant doomers.

I find it funny you say all this doomer shit, and then end with asking for sci fi book recommendations. Sci fi is the reason everyone thinks so negatively of the singularity. Try reading science, not fiction. It’s better for the mind

Do you mean like we won’t be humans anymore?

I suppose it will be tough to classify us as a species in the future for sure. Some people will be uploaded into the cloud, some people may remain biological meatbags.

Why do u dislike the term?

No 90% is specifically for drug development only. I don’t know the exact number 90% is just an estimate. But I’ve read AI speeds up drug discovery a ton.

And with full in silico models instead of clinical trials taking 10+ years, it will take 2-3 years instead. Pre clinical testing on the in silico model should take under a year, and then the phase 3 trial on humans should take 1-2 years.

So overall the entire process from developing a drug to getting it on the market could go from 15 years to under 5 years.

Look up Insilico medicine, I believe they are the company that uses AI the most for drug discovery. They already have a drug for idiopathic pulmonary fibrosis that was developed completely by AI

And organ on a chip models are already being used. Full scale in silico models not yet, but like I said maybe proto AGI enables that.

Development shortens the drug development pipeline by like 90%+, and in silico models could shorten trial process by years. Go straight to phase 3 human trials skip the previous steps etc

By itself probably not very capable. Working with humans it will speed things up. Narrow AI has already sped up drug discovery. AI is also bringing in silico human models for use in trials which should speed up drug development.

AGI is probably when it can do research on its own independent of human input. That will be a game changer

Great explanation!

You can’t use a whole country’s life expectancy to project your own. 70% of the US is overweight or obese. Decent amount smoke, do drugs, dont take vaccines, don’t take care of their health at all.

Family history of longevity (genetics) also matters a lot.

Social skills are similar to any other skills your brain learns, I believe AI will be able to simply input these skills into our brains

Gone are the days where some individuals are more skilled than others (socially, artistically, intelligence wise, physically etc). I think AI puts everyone on the same playing field

I genuinely think that people born in a decade or 2 will never experience going to school like the rest of us did for ~20 years

If they are merged with AI they will just learn everything automatically without needing to spend any time in education.

continue breathing and waiting