Time-Lime

Time-Lime t1_jaerb9i wrote

Reply to comment by prl853 in Immune cells called microglia, which keep the brain free of debris but also contribute to inflammation, are the likely culprits behind concentration and memory problems ("chemo brain") that sometimes follow paclitaxel chemotherapy treatment, a new study in mice suggests. by memorialmonorail

Well in long covid the theory is that they are stuck in an overactive state which isnt neccessary and only detrimental. So calming them down shouldnt have negative consequence as getting them out of this chronic state is good.

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Time-Lime t1_jaensyn wrote

Reply to Immune cells called microglia, which keep the brain free of debris but also contribute to inflammation, are the likely culprits behind concentration and memory problems ("chemo brain") that sometimes follow paclitaxel chemotherapy treatment, a new study in mice suggests. by memorialmonorail

Also a likely culprit behind some long covid symptoms (brain fog, concentration problems, anxiety etc) as covid crosses the blood brain barrier causing overactive microglia and neuroinflammation. Low dose naltrexone is a promising treatment for both chemo brain and long covid...guess what it can do. Yes! Modulate microglia and calm them down, in laymans terms.

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Time-Lime t1_izdlkr7 wrote

Reply to comment by Weird-Fox-4036 in A Swedish study of over 200,000 people who tested positive for SARS-CoV-2 between March 2020 and July 2021 has found that women, people with asthma and those with previous mental health disorders are more likely to experience long-term effects of COVID-19. by MistWeaver80

Yeah, although serotonin syndrome is very low risk as long as you dont mix with the wrong drugs/supplements haha...But yes there are risks. All about weighing up the potential benefits vs risks at the end of the day.

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Time-Lime t1_izdjzv0 wrote

Reply to comment by Weird-Fox-4036 in A Swedish study of over 200,000 people who tested positive for SARS-CoV-2 between March 2020 and July 2021 has found that women, people with asthma and those with previous mental health disorders are more likely to experience long-term effects of COVID-19. by MistWeaver80

This is all true and good advice. I would just like to add SSRI as another potential tool. SSRIs have significant anti-neuroinflammatory effects.

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Time-Lime t1_izdiqju wrote

Reply to comment by [deleted] in A Swedish study of over 200,000 people who tested positive for SARS-CoV-2 between March 2020 and July 2021 has found that women, people with asthma and those with previous mental health disorders are more likely to experience long-term effects of COVID-19. by MistWeaver80

No this is known. Ive posted about this before. But covid can cross the blood brain barrier. Causes neuroinflammation. Neuroinflammation is related to a whole host of mental health disorders including anxiety, OCD and depression. Covid can thus trigger or worsen these disorders.

SSRI has a significant anti-neuroinflammatory effect. Could be the main reason for their efficacy. People who take SSRIs have a lower risk of being severly ill from covid.

I dont have a lot of time thus the very short explanations and answers. I can back every single statement up with peer reviewed papers if anyone doubts me however. May add these as references after work.

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