Volume of distribution, time of ingestion, half life of medication, was it taken orally or parenterally, etc, etc, would need to be known.
Also whether this was dose 1 or if there were multiple doses.
But the equations only apply to live people. After death, considerable changes can occur -
Some drug concentrations go up, some go down, it’s not exactly predictable.
That being said, I haven’t really used pharmacokinetics and pharmacodynamics for years. Did you ask the person who performed the autopsy?
Historical-Piglet-86 t1_j6dpmfa wrote
Reply to Can you (roughly) determine the dosage of a drug taken based off of the blood concentration? by bynarie
Volume of distribution, time of ingestion, half life of medication, was it taken orally or parenterally, etc, etc, would need to be known.
Also whether this was dose 1 or if there were multiple doses.
But the equations only apply to live people. After death, considerable changes can occur - Some drug concentrations go up, some go down, it’s not exactly predictable.
That being said, I haven’t really used pharmacokinetics and pharmacodynamics for years. Did you ask the person who performed the autopsy?